时事万象 正评论:基因改造婴儿诞生 ...

正评论:基因改造婴儿诞生 潘朵拉魔盒已开

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【新三才独家首发评论】据中国传媒报道,南方科技大学生物系副教授贺建奎11月25日公开上传视频宣布,一对名为「露露」(Lulu)和「娜娜」(Nana)的基因编辑(gene editing)婴儿已经诞生。他创造了第一对基因编辑的双胞胎,改变了他们的DNA以保护他们免受艾滋病病毒的感染。

贺建奎告诉《美联社》,他为七对夫妇编辑了胚胎,而其中一对导致了怀孕。这对双胞胎女孩本月出生,他说他们的父母不想接受采访。「两个小中国女孩名叫露露和娜娜,几周前就像其他婴儿一样出生。」他在网上发布的视频中说道。「婴儿现在和他们的妈妈Grace和他们的父亲Mark一起回家。」

贺建奎说他使用了一种名为「CRISPR」的基因编辑工具,它允许科学家添加一个需要的基因或禁用导致问题的基因。它已在成人中尝试过,但编辑精子和卵子被认为是不同的,因为这些变化可以被遗传。这对双胞胎的父亲患有艾滋病病毒,但正在服用药物来抑制病毒变成艾滋病。DNA变化旨在通过禁用允许HIV进入细胞的基因来防止小孩未来的感染。

然而,最令人恐惧的是,贺建奎自己在视频中表示,虽然他知道自己的研究会引起争议,但他愿意这样做,因为他认为这样做是在「帮助」这些孩子以及其家庭,并且呼吁大家支持他的做法。就连中共官方《人民网》的深圳频道也报导称其为世界首例免疫爱滋病的基因编辑婴儿,意味中国在基因编辑技术用于疾病预防领域,实现历史性突破。

胚胎中的基因编辑类型在美国被禁止,除了在实验室研究期间,因为它可以影响后代并且有可能危害其他基因。中国虽然禁止克隆,但并未禁止基因编辑。基因改造人类胚胎是否符合道德及伦理一直是医学界一个引发争议的议题,英国等国家更禁止一切与改造人类基因有关的研究。

即使贺建奎的说法尚未在医学期刊上发表或被独立确认,但其研究传出后已经被外界强烈质疑,122名中国科学家11月26日更发表联合声明,批评研究直接进行人体实验「只能用疯狂来形容」,又呼吁中国政府「一定要迅速立法严格监管,潘多拉魔盒已经打开,我们可能还有一线机会在不可挽回前,关上它。」

当人试图越过上帝最后一道防线,扮演上帝脚色来对人类本身基因改造以控制人的生命,并且还认为可基于某种理由或原因(例如本案所谓的防止艾滋病感染),就可以有其合理性,甚至所谓的合法性,那人类继续发展下去,终究会因为人性的贪婪与私欲,而选择透过基因改造增强特定人们的智商、体能、个性,甚至外观等,不论如此的改造能否真正达到目的,抑或引发更无法预期的副作用,到时人们所要面临的,绝对不会是科学家所宣称的美丽新世界,反而是真正所谓的「不可挽回」的境地了。

(评论/责任编辑:姜启明)

(文章来源:新三才独家首发评论)

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